Research is fundamental to improving quality and care for everybody and patients often enjoy being part of these studies. Sometimes they receive tests or treatments that wouldn’t have been available to them otherwise and benefit from regular monitoring and close care.
Volunteering to get involved may mean filling in questionnaires, surveys, talking to one of the research team, or trialling a new treatment or drug.
All clinical research projects are checked by external ethical committees, before being offered to the Research Team. We then select those projects that interest us or are most relevant to our practice population.
There are various ways that you can become involved in studies:
A doctor or nurse may talk to you about a particular study and ask whether you would be interested in participating
You may be sent information through the post if we feel you may be a suitable participant
You may see information within the practice, via our practice website or social media channels and wish to find out more information about taking part
Your participation is entirely voluntary and can be withdrawn by yourself at any time.
You will always receive clear information about what taking part in a research study would involve. You will have the opportunity to ask questions and obtain further details about a study.
If you do agree to take part in a study you will be asked to sign a consent form. This will clearly state which parts of your notes (if any) may be looked at for the purposes of the research study. Nobody from outside this practice will be given your contact details or have access to your medical records without your prior consent.
People who have received the vaccination are still eligible to join the PRINCIPLE trial in search of treatments.
To take part, you need to:
You have had a positive test for COVID-19, AND are unwell with symptoms of COVID-19 which have started in the last 14 days. These symptoms may include, but are not limited to:
a new continuous cough – this means coughing a lot for more than an hour, or 3 or more coughing episodes in 24 hours (if you usually have a cough, it may be worse than usual),
a high temperature – this means you feel hot to touch on your chest or back (you do not need to take your temperature),
a loss of, or change in, normal sense of taste or smell
shortness of breath,
general feeling of being unwell,
muscle pain, diarrhoea,
vomiting, fever and cough,
and you must have had them for fewer than 15 days.
The study is for people with ongoing symptoms. People who feel they are already well on the way to recovery should not take part.
You also need to be aged 18 and over
Find out more https://www.principletrial.org/
Semaglutide effects on heart disease and stroke in patients with overweight or obesity
The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo (“dummy” medicine). Which treatment the participants get is decided by chance. The participant’s chance of getting semaglutide or placebo is the same. The participant will get the study medicine in a pen. The participants will need to use the pen to inject the study medicine in a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have up to 25 clinic visits with the study doctor.
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.
Are you interested in taking part in a GlaxoSmithKline sponsored study looking at the use of a vaccine to prevent another shingles attack in the future?
If you’re aged 50 and over, and have had Shingles once before please get in touch.
The Active Brains Study
A quick summary of the study
·This study is testing an interactive programme (called ‘Active Brains’) to help people aged 60-85 with lifestyle changes and brain training activities which may help with memory and thinking skills.
·If you take part, the study will last for five years.
·We ask everyone who takes part to complete 4 online puzzle games and answer some questions about how they are when they start the study, and then again each year after that. Doing these online puzzle games each year is a really important part of the study, and only takes about 10 minutes.
·About two thirds of people will be in a group who can use Active Brains straight away and one third of people will carry on with usual care and get brief advice about a healthy lifestyle.
·Which group you are in will be decided by chance.
·Everyone in the study will carry on receiving their usual NHS care.
·The activities recommended by Active Brains can nearly all be done at home. They are all activities that are likely to be good for staying fit and healthy in general. However, it is very important to follow current government advice about how to stay safe and healthy during the Coronavirus (COVID-19) outbreak.
The study is being run by the University of Southampton and is funded by the National Institute for Health Research, the main funder of research in the NHS.
PANDA-S: Prognostic AND Diagnostic Assessment of Shoulder Pain research study
Shoulder problems affect 20% of adults and are often very painful, affecting sleep, work, and everyday life. Most patients receive treatment from GPs or physiotherapists, but 7 times more patients are having surgery compared with 10 years ago. There is no evidence that surgery provides better results than non-surgical treatments such as shoulder exercises.
In order to develop and test a better approach to assessing the likely cause (diagnosis) and future outcome (prognosis) of shoulder problems we aim to recruit 1000 patients consulting their GP or self-referring to physiotherapy with shoulder pain to a follow-up study. Their GPs and physiotherapists will continue to treat them in the way they feel is most appropriate. Willing participants will complete 6 questionnaires on pain, difficulties with everyday activities, treatments, and quality of life over 3 years, providing unique information about long-term outcomes. They will also be invited to attend an optional clinical assessment including an ultrasound scan of the shoulder and/or complete an optional app or respond to text messages once a week for 12 weeks to provide short term information on shoulder pain and difficulties with everyday activities. They will additionally be invited to participate in an optional interview about their shoulder pain.
Aim “The aim of this trial is to compare the effectiveness and cost effectiveness of brief messaging to support patients with type 2 diabetes taking diabetes medicine (glucose, blood pressure, or lipid lowering) in reducing risk factors for diabetes complications, with usual care”
Expression of interest
Text Register first & last name (e.g. Register John Smith) to 07800 002507
*If EOI received by email or telephone patients will be asked to text their full name. Participants MUST NOT be randomised unless a text has been receive
PROMDEP RCT (Patient-reported outcome measures for monitoring primary care patients with depression: PROMDEP randomised controlled trial)
The PROMDEP RCT will look at whether giving personal feedback to people being treated for depression might help them get better more quickly. This will be done by using the PHQ-9 depression symptom questionnaire as a patient reported outcome measure (or ‘PROM’) and feeding back the results to the patients themselves, and the practitioners looking after them, together with brief suggestions for treatment relevant to the severity of the patient’s depression.
The aim is to answer the following research question: What is the effectiveness and cost- effectiveness of assessing primary care patients with depression or low mood soon after diagnosis and again at follow-up 10-35 days later, using the PHQ-9 questionnaire combined with patient and practitioner feedback and guidance on treatment?