To be eligible to join the trial you will need to have experienced symptoms that are likely to be caused by COVID-19 for fewer than 15 days.
The trial is open to people aged over 65 or over, or aged 50-64 with an underlying health condition.
The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo (“dummy” medicine). Which treatment the participants get is decided by chance. The participant’s chance of getting semaglutide or placebo is the same. The participant will get the study medicine in a pen. The participants will need to use the pen to inject the study medicine in a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have up to 25 clinic visits with the study doctor.
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.
Have you had Shingles in the past?
Are you interested in taking part in a GlaxoSmithKline sponsored study looking at the use of a vaccine to prevent another shingles attack in the future?
If you’re aged 50 and over, and have had Shingles once before please get in touch.
Renewed online -Researchers at the University of Southampton have developed a resource ‘renewed online’ which supports people who have finished treatment for breast, bowel or prostate cancer, or people on active surveillance. There is advice on improving physical health and help with feelings of tiredness or stress and concerns about cancer.
Shoulder problems affect 20% of adults and are often very painful, affecting sleep, work, and everyday life. Most patients receive treatment from GPs or physiotherapists, but 7 times more patients are having surgery compared with 10 years ago. There is no evidence that surgery provides better results than non-surgical treatments such as shoulder exercises.
In order to develop and test a better approach to assessing the likely cause (diagnosis) and future outcome (prognosis) of shoulder problems we aim to recruit 1000 patients consulting their GP or self-referring to physiotherapy with shoulder pain to a follow-up study. Their GPs and physiotherapists will continue to treat them in the way they feel is most appropriate. Willing participants will complete 6 questionnaires on pain, difficulties with everyday activities, treatments, and quality of life over 3 years, providing unique information about long-term outcomes. They will also be invited to attend an optional clinical assessment including an ultrasound scan of the shoulder and/or complete an optional app or respond to text messages once a week for 12 weeks to provide short term information on shoulder pain and difficulties with everyday activities. They will additionally be invited to participate in an optional interview about their shoulder pain.
Are you 45 or older? Do you experience knee pain?
If you answered yes to both of the above questions, then you may be eligible to take part in the PROP-OA study – a clinical trial that is testing advice, exercise and knee braces in older adults.
Please explore this website to find out more information about the PROP-OA trial. To see if you can take part please call the PROP-OA research team on Freephone 0800 130 3419.
Is a research register that anyone over 18yrs can sign up, if they are interested in hearing about and
taking part in Irritable Bowel Syndrome (IBS) research.
The CHICO study is aiming to improve the treatment and care of children attending GP practices with coughs and acute respiratory tract infection (RTI).
The PROMDEP RCT will look at whether giving personal feedback to people being treated for depression might help them get better more quickly. This will be done by using the PHQ-9 depression symptom questionnaire as a patient reported outcome measure (or ‘PROM’) and feeding back the results to the patients themselves, and the practitioners looking after them, together with brief suggestions for treatment relevant to the severity of the patient’s depression.
The aim is to answer the following research question: What is the effectiveness and cost- effectiveness of assessing primary care patients with depression or low mood soon after diagnosis and again at follow-up 10-35 days later, using the PHQ-9 questionnaire combined with patient and practitioner feedback and guidance on treatment?
To get in touch: Email: PROMDEP@liverpool.ac.uk
If you would like to discuss or get involved in any of our research projects, please contact us
Please note that we are unable to advertise every study that we are doing, as this is sometimes due to the nature of the study design.